Presently, the Division is focusing its research thrust in 3 main areas namely Growth and Reproductive Physiology, Lactation and Immuno Physiology, and Environmental and stress Physiology.
Important research findings and Technologies (not more than 20)
• Development of sensitive radio-immunoassays for several protein and steroid hormones; development and validation of sensitive enzyme immunoassays for progesterone, oxytocin, GH, LH, FSH and PGFM
• Application of progesterone measurement in body fluids for fertility improvement viz. estrus confirmation, pregnancy/non pregnancy detection, monitoring cyclicity and identification of ovarian disorders, application of estrone sulphate determination in milk for confirmation of pregnancy and fetal viability.
• Indigenous production of progesterone antiserum and anti-rabbit IgG (second antibody) and their application in hormone immunoassays.
• Parturition induction, super ovulation and embryo transfer; neonate physiology; temporal endocrine interrelationships during different phases of growth, reproduction and lactation.
• Application of endocrine techniques for growth enhancement and fertility improvement, optimum frequency of feeding and milking.
• Induction of lactation, augmentation of lactation through Growth Hormone administration, estimates of udder capacities, residual milk and milk secretion rates.
• Limit of milk SCC set for Sahiwal, Tharparkar cows and Murrah buffaloes.
• Draught evaluation system, work efficiency of crossbred and indigenous bovine and buffalo bullocks and optimum work-rest cycle for working bullocks.
• Neutrophils in tissue remodelling, wound healing, maintaining homeostasis around transition, mastitis and during implantation of embryo in dairy cows.
Modulating the immune-cellular components and their signalling molecules in bovine colostrum and milk after micro-nutrient interventions and their functional validation under ex-vivo and in vivo animal models (DBT )
• To study the effect of micronutrient supplementation on immune cells and their signaling molecules in colostrum, transitional and normal milk of bovines.
• To assess the role of modified colostrum and milk in the alleviation of immunocompromised situation in calf and mice models.
Neutrophils as potential biomarkers/ predictors of early pregnancy in cows (DBT)
• To identify abundantly expressed pregnancy associated genes and proteins on neutrophils during early pregnancy
• Targeting neutrophil early pregnancy induced proteins for development of an ELISA for early pregnancy diagnosis