• Dr Prabhat Palta

    Dr Prabhat Palta
    Principal Scientist

    PS and In-Charge, Animal Biotechnology Centre, National Dairy Research Institute, Karnal-132001, Haryana

    • Current Research Area
      Reproductive biotechnology

    Qualifications:

    • M.Sc. (Animal Biochemistry)
    • Ph.D. (Animal Biochemistry)

    Major Research Accomplishments

    Guidance to student ( M.Sc. and Ph. D. ):

    Guided /currently guiding  7 M.Sc. and 5 Ph.D. students

    Awards:

    • Awarded the prestigious AJAS Purina Outstanding Research Award by the South Korea-based Asian Australasian Association of Animal Production Sciences in the area of Animal Reproduction.
    • ICAR Award for Outstanding Interdicplinary Team Research in Agricultural and Allied sciences (2013-14).
    • More than 15 Best Paper/Best Poster Awards

    Training:

    • Received training on gene targeting to stem cells at Institut fur Nutztiergenetik (Formerly Institut fur Tierzucht) at Mariensee, Neustadt, Germany from February 24, 2008 to May 23, 2008.

    Patents, Technology, Methodology, Genetic Stock, Variety, etc.:

    • Production of embryonic stem cells
    • In vitro production of embryos
    • Inhibin-based fecundity vaccines for sheep
    • Radioimmunoassay for various steroid and protein hormones
    • Animal cloning technology
    • Production of transgenic embryos

    Publications:

    • Selokar NL, Saini M, Palta P, Chauhan MS, Manik RS, Singla SK. (2018). Cloning of Buffalo, a Highly Valued Livestock Species of South and Southeast Asia: Any Achievements? Cellular Reprogramming 20(2):89-98.
    • Ashok D, Sood TJ, Sah S, Palta P, Mukesh M, Chauhan MS, Manik RS, Singla SK. (2018). Buffalo SCNT embryos exhibit abnormal gene expression of ERK/MAPK pathway and DNA methylation. Reproduction in Domestic Animals. doi: 10.1111/rda.13217.
    • Agrawal H, Selokar NL, Saini M, Singh MK, Chauhan MS, Palta P, Singla SK, Manik RS. (2018). Epigenetic alteration of donor cells with histone deacetylase inhibitor m-carboxycinnamic acid bishydroxymide improves the in vitro developmental competence of buffalo (Bubalus bubalis) cloned embryos. Cellular Reprogramming 20(1): 76-88.
    • Mehta P, Kaushik R, Singh KP, Sharma A, Singh MK, Chauhan MS, Palta P, Singla SK, Manik RS. (2018). Establishment, growth, proliferation, and gene expression of buffalo (Bubalus bubalis) transgenic fetal fibroblasts containing human insulin gene, and production of embryos by handmade cloning using these cells. Cellular Reprogramming 20(2):135-143.
    • Agrawal H, Selokar NL, Saini M, Singh MK, Chauhan MS, Palta P, Singla SK, Manik RS. (2018). m-carboxycinnamic acid bishydroxamide improves developmental competence, reduces apoptosis and alters epigenetic status and gene expression pattern in cloned buffalo (Bubalus bubalis) embryos. Reproduction in Domestic Animals 53(4):986-996.
    • Sood TJ, Lagah, V.S., Sharma, A., Singla, S.K., Mukesh, M., Chauhan, M.S., Manik, R.S., and Palta, P. (2017). Selection of suitable internal control genes for accurate normalization of real-time quantitative PCR data of buffalo (Bubalus bubalis) blastocysts produced by SCNT and IVF. Cellular Reprogramming 19(5): 302-310.
    • Selokar NL, Saini M, Agrawal H, Palta P, Chauhan MS, Manik R, Singla SK. (2017). Valproic acid increases histone acetylation and alters gene expression in the donor cells but does not improve the in vitro developmental competence of buffalo (Bubalus bubalis) embryos produced by hand-made cloning. Cellular Reprogramming 19(1):10-18.
    • Shah, S.M., Singla, S.K., Palta, P., Manik, R.S. and Chauhan, M.S. (2017). Retinoic acid induces differentiation of buffalo (Bubalus bubalis) embryonic stem cells into germ cells. Gene 631: 54-67.
    • Shah SM, Saini N, Ashraf S, Singh MK, Manik RS, Singla SK, Palta P, Chauhan MS. (2017). Cumulus cell-conditioned medium supports embryonic stem cell differentiation to germ cell-like cells. Reproduction Fertility and Development 29(4):679-693.
    • Saini M, Selokar, NL, Agrawal, H, Singla, SK, Chauhan, MS, Manik, RS and Palta P. (2017). Treatment of donor cells and reconstructed embryos with a combination of trichostatin-A and 5-aza-2’-deoxycytidine improves the developmental competence and quality of buffalo embryos produced by handmade cloning and alters their epigenetic status and gene expression. Cellular Reprogramming 19(3): 208-215.