• Dr. Archana Verma

    Dr. Archana Verma
    Principal Scientist

    Animal Genetics & Breeding Division, ICAR-NDRI, Karnal

    • Current Research Area
      Molecular Genetics & Genomics

    Qualifications :

    • M.Sc.
    • Ph.D.

    Major Research Accomplishments:

    • Genetic variation in a number of candidate genes related to milk production & composition(GH, Beta-lactoglobulin, alpha-casein, beta-casein, kappa-casein, leptin, prolactin, ATF4 (Activating Transcription Factor 4),OLR1 (Oxidized low density lipoprotein receptor 1 ),SOCS2 (Suppressor of Cytokine Signalling 2),CRH (Corticotrophin Releasing Hormone); reproduction (BSP5 (Binder of Sperm5), ODF1 (Outer dense fiber of sperm tail 1),PLCZ1 (Phospholipase C zeta 1), ZNF280BY (Zinc finger protein 280BY), PROP1 (Prophet of PIT1), SPAG11, ITGB5, protein phosphtase1 regulatory subunit 11 (PPP1R11), heat shock proteins(HSP27, HSP90AA1, HSPB1, HSF1); mastitis (lactoferrin, Interleukin-8 (IL-8),  Toll-like receptor 4 gene (TLR 4), Forebrain embryonic zinc finger like gene (FEZL), Caspase activating recruitment domain 15 gene (CARD 15), Calgranulin gene (S100A8), Cluster of Differentiation 14 (CD 14) gene, Mannose binding lectin (MBL1, MBL2) C4A); and type traits (GC (GC, vitamin D binding protein), NPFFR2 (neuropeptide FF receptor 2), PRLR (Prolactin receptor), FAM19A1 (family with sequence similarity 19 member A1, C-C motif chemokine like), KCNB1 (potassium voltage-gated channel subfamily B member 1), EDN3 (endothelin 3)have been explored and their association has been established in indigenous and crossbred cattle and Murrah buffalo.
    • Genome-wide SNPs and SSRs have been identified in Gir and Tharparkar cattle.
    • Genome-wide association study with milk production in Murrah buffaloes is in progress.

    Research Projects:

    • Institute: 5 (3 as PI)
    • Externally Funded: 2 (as co-PI)

    Teaching:

    M.V.Sc.:

    • AG-611 (Animal Cytogenetics and Immunogenetics)
    • AG-621 (Molecular Genetics in Animal Breeding)

    Ph.D.:

    • AG-711 (Recent Advances in Animal Genetics)
    • AG-722 (Advances in Molecular Cytogenetics)

    Students Guided:

    • M.Sc./M.V.Sc.: 19 + 3 (presently working)
    • M.Phil./Ph.D.: 14 +1 (presently working)

    Students Guided:

    • M.Sc./M.V.Sc.: 19 + 3 (presently working)
    • M.Phil./Ph.D.: 14 +1 (presently working)

    Transfer of Technology:

    • ‘Detection of buffalo milk in cow milk using Hansa Test Serum’ transferred to M/s Mother Dairy, New Delhi

    Patents, Technology, Methodology, Genetic Stock, Variety, etc.:

    • A total of 123 Gene Bank Accession Numbers have been received for a number of genes in Sahiwal cattle and Murrah buffaloes.

    Publications:

    • Azad M. S., I. D. Gupta, Archana Verma, Raja. K. N, Ritwik Hazra and Rajesh Kumar S 2012. Detection of coagulation factor XI gene deficiency in Sahiwal cattle. The Indian Veterinary Journal. 89 (6):61-62.
    • Datta Sanjoy, Archana Verma, I. D. Gupta, Indrasen Chauhan, Mandeep S. Azad, Yathish H.M., N. K. Batul, and T. Har. 2012. Identification of polymorphism in leptin gene of Murrah buffalo by PCR-RFLP. Exploratory Animal and Medical Research 2 (1) : 7-17
    • Datta Sanjoy, AMJB Adhikari, Anuj Chauhan, Archana Verma, I.D. Gupta, Inderasen Chauhan, Mandeep S. Azad and Yatish H. M. 2012. Nucleotide Sequence Variation in Leptin Gene of Murrah Buffalo (Bubalus bubalis). Exploratory Animal and Medical Research 2 (2): 130-136.
    • Manoj M, Gandhi R.S, Raja T.V, Verma Archna, Singh Avtar and Sachdeva Gk 2012. Growth rates and growth curve in Sahiwal cattle 2012. Indian Journal of Dairy Science 65 (4): 354-355.
    • Raja K. N., Gupta. I. D. and Archana Verma. 2012. Single strand conformation polymorphism at 5’ flanking region of lactoferrin gene in Sahiwal cattle. The Indian Veterinary Journal 89 (9): 16-18.
    • Soumya N. P., D. Gupta, Archana Verma, K. N. Raja, Inderasen Chauhan, Mahesh Chaudhari and R. S .Wakchaure. 2013. Identification of CARD-15 Gene Polymorphism in Sahiwal Cattle. Indian J. Anim. Res. 47 (1): 83-86.
    • Verma Archana, Gupta I D and Gandhi R S. 2012. Genetic polymorphism in exon 3 of prolactin gene in Indian Murrah buffaloes. Wayamba Journal of Animal Science. http://www.wayambajournal.com, DOI 1337018272.
    • Virendra Kumar, D. Gupta, Archana Verma, S. Rajesh Kumar and M.V. Chaudhari. 2013. CD14 Gene Polymorphism using HinfI RE and its Association with Mastitis in Sahiwal Cattle. India J. Anim. Res. (Accepted vide No. ARCC/B-2535).
    • Wakchaure R.S., I. D. Gupta, Archana Verma, Dinesh Kumar and Rajesh Kumar S. 2012. PCR-RFLP with Alu I RE enzyme in TLR4 gene of Sahiwal Cattle. Indian J. Anim. Res. 46 (2): 205-207.
    • Wakchaure R. S., I. D. Gupta, Archana Verma, Dinesh Kumar and G. S. Sonwane. 2012. Association of Genetic Variants of Partial Exon 3 Region of TLR4Gene with Mastitis in Sahiwal Cattle”. Indian J. Anim. Res. 46 (2): 208-209.
    • Archana Verma (2013) Nucleotide sequence variability in exon 4 of prolactin locus in Murrah buffaloes (Bubalus bubalis). Research Journal of Biotechnology 8 (6):61-65.
    • Sanjoy Datta, Archana Verma, Paresh Chatterjee and Aruna Pal Chatterjee (2013) Molecular characterization of the leptin gene in riverine buffaloes. Buffalo Bulletin (Thailand). 32(3): 196-211.
    • Alka Chopra, I. D. Gupta, Archana Verma, Soumya N. P. and V. Vohra (2013) Identification of Lactoferrin gene Polymorphism and its association with Mastitis incidence. Journal of Animal Research, 3 (1): 103-108.
    • Wakchaure, R. S., I. D. Gupta, Archana Verma, Dinesh Kumar and Rajesh Kumar S. (2013) PCR-RFLP with Alu I Restriction Enzyme in TLR4 Gene of Sahiwal Cattle. Indian J. Anim. Res. 47 (2): 172-174.
    • Indrasen Chauhan, Archana Verma, Ishwar Dayal Gupta and Gokul S. Sonawane (2013) Genetic Polymorphism in Caspase Activating Recruitment Domain 15 and its Association with Incidence of Mastitis in Murrah Buffalo. Buffalo Bulletin, 32 (Special Issue 2): 723-728.
    • Archana Verma, Ishwar Dayal Gupta and Ravinder Singh Gandhi (2013) Genetic Variability in Production and Immune Function Genes Associated with Production Traits and Incidence of Mastitis in Indian Murrah Buffalo. Buffalo Bulletin, 32 (Special Issue 2): 729.
    • Alka Chopra, I. D. Gupta, Archana Verma and V. Vohra (2014). PCR-RFLP analysis of bovine lactoferrin promoter and its association with mastitis incidence in crossbred (Karan Fries) cattle. The Indian J. Vet. Sci. 2(1): 34-38.
    • P. Soumya, I. D. Gupta, Archana Verma, K. N. Raja, Inderasen Chauhan, Mahesh Chaudhari and R. S .Wakchaure. (2013). Identification of CARD-15 Gene Polymorphism in Sahiwal Cattle. Indian J. Anim. Res. 47 (1): 83-86.
    • Alka Chopra, I. D. Gupta, Archana Verma and V. Vohra (2014). Detection of Allelic Variants in Lactoferrin gene promoter using Created Restriction Site PCR-RFLP and its Association with Mastitis. The Indian Journal of Animal Sciences 84 (10): 1068-1070.
    • Raja K. N., Gupta. I. D. and Archana Verma (2014). Sequence characterization of lactoferrin gene promoter region in Bos indicus cattle. Indian J. Anim. Res. 48 (1): 6-10.
    • Virendra Kumar, I. D. Gupta, Archana Verma, S. Rajesh Kumar and M. V. Chaudhari (2014). CD14 gene polymorphism using Hinf restriction enzyme and its association with mastitis in Sahiwal cattle. Indian J. Anim. Res., 48 (1): 11-13.
    • Sakthivel Selvan, I. D. Gupta, Archana Verma, Mahesh V. Chaudhari, Shishir Kanungo and S. Rajesh Kumar (2014). Characterization of promoter region of CD14 gene and Association with clinical mastitis in Karan Fries cattle. Indian J. Anim. Res.,48 (6): 545-547.
    • Selvan A.S., Gupta I.D., Verma A., Chaudhari M.V., Kumar V. (2014) Cluster of differentiation 14 gene polymorphism and its association with incidence of clinical mastitis in Karan Fries cattle. Veterinary World 7(12): 1037-1040.
    • Arya Ashwani, Archana Verma, I. D. Gupta, Shahid A. Shergojry, Ankit Magotra, Dhaman Kumar and Arun P. Singh (2015) Molecular characterization and SNP identification in HSPB1 gene in Murrah buffalo. Indian Journal of Animal Research. 48 Online Published Date: 2015-03-10 DOI: 10.5958/0976-0555.2015.00035.7
    • Chakraborty Dibyendu, Singh Avtar, Tantia MS, Verma Archana and Chakravarty AK. 2015. Genetic polymorphism of BOLA-DRB 3.2 locus in Sahiwal cattle.Animal Science Reporter. 9(1): 33-40.
    • Chopra Alka, I. D. Gupta, Archana Verma and V. Vohra (2014). Detection of Allelic Variants in Lactoferrin gene promoter using Created Restriction Site PCR-RFLP and its Association with Mastitis. The Indian Journal of Animal Sciences 84 (10): 1068-1070
    • Chopra Alka, I. D. Gupta, Archana Verma and V. Vohra (2014). PCR-RFLP analysis of bovine lactoferrin promoter and its association with mastitis incidence in crossbred (Karan Fries) cattle. The Indian Journal of Vet. Sci.  2(1): 34-38. ijmanager.org/ index.php/ijvs
    • Das Ramendra, I. D. Gupta, Archana Verma, Avtar Singh, Mahesh V Chaudhari, Lalrengpuii Sailo, R. C. Upadhyay, J. Goswami (2015). Genetic polymorphisms in ATP1A1 gene and their association with heat tolerance in Jersey crossbred cows. Indian J. Dairy Sci. 68(1): 50-54.
    • Lalrengpuii Sailo, I. D. Gupta, Archana Verma, Avtar Singh, Mahesh Vishwas Chaudhari, Ramendra Das, R.C. Upadhyay, Goswami (2015). Single nucleotide polymorphism in HSP90AB1 gene and its association with thermo-tolerance in Jersey crossbred cows. Animal Science Reporter 9(2):43-49
    • Manoj M, Gandhi R S, Raja TV, Verma Archana, Singh Avtar, Sachdeva GK and Amit Kumar. 2014. Genetic Parameters of body weights at different ages in Sahiwal Heifers. Indian Journal of Animal Research. 48 (3): 217-220.
    • Selvan A.S., Gupta I. D., Verma A., Chaudhari M. V., Kumar V. (2014) Cluster of differentiation 14 gene polymorphism and its association with incidence of clinical mastitis in Karan Fries cattle, Veterinary World 7(12): 1037-1040.
    • Selvan Sakthivel, Gupta I.D., Archana Verma, Mahesh V. Chaudhari, Shish Kanungo and S. Rajesh Kumar (2014). Characterization of promoter region of CD14 gene and Association with clinical mastitis in Karan Fries cattle. Indian J. Anim. Res.,48 (6): 545-547.
    • Krishanender Dinesh, Archana Verma, I. D. Gupta, Y. P. Thakur, NishantVerma and AshwaniArya (2015). Identification of polymorphism in exons 7 and 12 of lactoferrin gene and its association with incidence of clinical mastitis in Murrah buffalo. Tropical Animal Health and Production 47: 643-647.
    • Ashwani Arya, Archana Verma, I D Gupta, Shahid A Shergojry, Ankit Magotra, Dhaman Kumar and Arun P Singh (2016)  Molecular Characterization and SNP Identification in HSPB1 Gene in Murrah Buffalo. Indian Journal of Animal Research 50 (4): 645-649
    • Ashwani Arya, Archana Verma, I D Gupta, Dhaman Kumar, Ankit Magotra, Mohsin A. Mir and Arun P Singh (2016) Influence of parity, THI and HSPB1 gene SNP on heat tolerance indicator traits in Murrah buffalo (Bubalus bubalis). Ruminant Science 5 (2): 143-148.
    • Lalrengpuii Sailo, I D Gupta, Archana Verma, Ramendra Das, M V Chaudhari, Sohanvir Singh(2016) Polymorphisms in HSP90AB1 gene and their association with heat tolerance in Sahiwal and Karan Fries cows. Indian Journal of Animal Research 50 (6): 856-861.
    • NishantVerma, IshwarDayal Gupta, Archana Verma, Rakesh Kumar, Ramendra Das and Vineeth M R (2016)Novel SNPs in HSPB8 Gene and their Association with Heat Tolerance Traits in Sahiwal Indigenous Cattle. Tropical Animal Health and Production 48(1): 175-18.
    • Rakesh Kumar, Ishwar Dayal Gupta, Archana Verma,Sohan Vir Singh, Nishant Verma, M R Vineeth, Ankit Magotra and Ramendra Das (2016) Novel SNP Identification in Exon 3 of Hsp90AA1 Gene and their Association with Heat Tolerance Traits in Karan Fries (Bos Taurus × Bos indicus) Cows under Tropical Climatic Condition. Tropical Animal Health and Production. 48 (4): 735-740
    • Rakesh Kumar, Ishwar Dayal Gupta, Archana Verma,  Nishant Verma and  Vineeth M.R. (2017) Single nucleotide polymorphisms in Heat Shock Protein HSP90AA1 gene and their association with heat tolerance traits in Sahiwal cows. Indian J Animal Research 51 (1): 64-69.
    • Ramendra Das,  IshwarDayal Gupta, Archana Verma,  Sohanvir Singh, Mahesh Vishwas Chaudhari ,  Lalrengpuii Sailo,  Nishant Verma and Rakesh Kumar (2017) Single nucleotide polymorphisms in ATP1A1 gene and their association with thermo-tolerance traits in Sahiwal and Karan Fries cattle. Indian Journal of Animal Research 51 (1): 70-74.
    • Sourabh Sulabh, Archana Verma and D. Gupta (2016) Genotyping of Calgranulin A Gene in Murrah Buffaloes by PCR-RFLP. Indian Journal of Dairy Science. 69 (2): 178-181.
    • Sourabh Sulabh, Archana Verma, I D Gupta and S Rajesh Kumar  (2016) Detection of Polymorphism of Calgranulin A Gene in Indian Murrah Buffalo. Indian Journal of Animal Research: 50 (5): 658-661.
    • Sourabh Sulabh, Archana Verma, I D Gupta and Bharat Kumar (2018) Novel SNPs in DGAT1 gene and their association with milk traits in Murrah buffaloes. Indian J Dairy Sci 71(2):187-192.